Research and Reports in Gastroenterology

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The Relation between Helicobacter Pylori Infection, Serum Ammonia and Hepatic Encephalopathy in Yemeni Cirrhotic Patients

Introduction: Helicobacter pylori (H. pylori) infection in the group of patients with liver cirrhosis may affect the exacerbation of inflammatory injuries in the stomach, which could directly, and indirectly, lead to loss of liver function.
Aim of the study: Assessment of possible relation among H. pylori infection, serum ammonia, and hepatic encephalopathy in the middle of patients with liver cirrhosis.
Patients and methods: This study was conducted in the Hepatobiliary-Gastroenterology Specialized Research Center in Sana'a City Yemen. This is a prospective study and patients from April 2008 to April 2014 were collected. All patients with established Chronic Liver Disease (CLD) with hepatic encephalopathy.
Result:A total of 78 patients with liver cirrhosis included in the present study, there were selected, (n=42; 54%) were males and (n=36; 46%) were females. Clinical and demographic characteristics of the study patients were shown H.E grade had the most significant relationship with H. pylori state (p=0.000). There was a significant relation between stage A, B, C, and H. pylori state (p=0.09).
Conclusion:This study comes to more reliable and confident that is a highly significant association among H. pylori infection, Hepatic Encephalopathy, stage A, B, C, and serum ammonia in cirrhotic patients.

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