Humongous Ovarian Serous Cystadenoma in a Postmenopausal Woman

Humongous ovarian neoplasm that is greater than 10 cm is a rare finding due to the availability of advanced imaging modalities. We present the case of a 50-year-old postmenopausal woman who presented to the emergency department complaining of recurrent ground level falls and increasing abdominal girth over the past 2 years, however, with rapid growth over the past six months. Computed tomography of the abdomen and pelvis demonstrated a large mixed, solid, round and hyperdense mass measuring 54 cm craniocaudal x 41 cm transverse x 50 cm anteroposterior in size. Our patient underwent an emergent exploratory laparotomy with excision of abdominopelvic mass, total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histopathological evaluation of mass suggested a benign serous cystadenoma. To our knowledge, this is the largest reported cystadenoma since the mid-20th century. Our case highlights the multidisciplinary approach of a rare and high-risk case and the importance of addressing healthcare disparities and access to medical care.