Treatment strategies and outcome in locally advanced oral cancer extending to infra temporal fossa

Locally advanced oral cancers extending to infratemporal fossa staged T4b were regarded inoperable till 2006, and received palliative treatment. From 2007, few institutions ventured into compartment resection of infratemporal fossa for patients with infratemporal fossa involvement. We treated 60 patients with compartment resection of infratemporal fossa with control rates of 59%. We conducted randomized study to compare outcome of treatment following upfront surgery and Neoadjuvant chemotherapy plus surgery for these patients. Results, recommendations and morbidity will be presented.