International Journal of Ophthalmic PathologyISSN: 2324-8599

Research Article, Int J Ophthalmic Pathol Vol: 2 Issue: 4

Assessment of the Anterior Chamber Angle after Trabectome Glaucoma Surgery by Optical Coherence Tomography, Histopathology, Ultrasound Biomicroscopy, and Scanning Electron Microscopy

Jeremy C Hwang1, Kay T Khine2, Narsing A Rao1, Don S Minckler3, Farnaz Memarzadeh1, Yan Li4, David Huang4, Brian A Francis1*
1Doheny Eye Institute, Department of Ophthalmology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
2Brody School of Medicine, East Carolina University, Greenville, NC, USA
3Gavin S. Herbert Eye Institute, Department of Ophthalmology, University of California, Irvine, USA
4Casey Eye Institute, Department of Ophthalmology, Oregon Health & Science University, Portland, OR, USA
Corresponding author: Brian Francis
Doheny Eye Institute, 1450 San Pablo Street, DEI 4804, Los Angeles, CA 90033, USA
Tel: 323-442-6454; Fax: 323-442-6412
E-mail: [email protected]
Received: September 27, 2012 Accepted: October 03, 2013 Published: October 17, 2013
Citation: Hwang JC, Khine KT, Rao NA, Minckler DS, Memarzadeh F, et al. (2013) Assessment of the Anterior Chamber Angle after Trabectome Glaucoma Surgery by Optical Coherence Tomography, Histopathology, Ultrasound Biomicroscopy, and Scanning Electron Microscopy. Int J Ophthalmic Pathol 2:4. doi:10.4172/2324-8599.1000125

Abstract

To provide high resolution in vitro and in vivo characterization of the post-trabectome anterior chamber angle. We used scanning electron microscopy (SEM) to obtain high resolution images of the post-trabectome angle in cadaver eyes. We then characterized trabecular meshwork strips removed during the procedure using histopathology. Finally,we imaged the post-Trabectome angle in two patients using optical coherence tomography (OCT) and ultrasound biomicroscopy(UBM).

Keywords: Trabectome; Post-trabectome anterior chamber angle; Trabecular cleft; Trabecular beams; Schlemm's canal; Trabecular meshwork; Trabeculectomy ab interno

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