Journal of Clinical & Experimental OncologyISSN: 2324-9110

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Case Report, J Clin Exp Oncol Vol: 3 Issue: 4

Atipic Axillary Mass: Follicular Dendritic Cell Sarcoma within Castleman's Disease: A Case Report and Review of Literature

Maite Lopez Deogracias1*, Ricardo González Cámpora2, Ilde Zamacola Aristegi3, Iñaki Arias-Camison3, Francisco Martínez García1
1Department of General Surgery(Clínica Asunción)
2Department of Pathology(Hospital Universitario Virgen de la Macarena)
3Department of Pathology (Clínica Asunción, Guipúzcoa, Spain)
Corresponding author :Maite Lopez
Clínica Asunción, Ctra Izaskun s/n, 20400 Tolosa, Guipúzcoa, Spain
Tel: +966- 608321963
Received: November 03, 2014 Accepted: December 16, 2014 Published: December 22, 2014
Citation: Maite LD, Ricardo GC, Ilde ZA, Iñaki AC, Francisco MG (2014) Atipic Axillary Mass: Follicular Dendritic Cell Sarcoma within Castleman’s Disease: A Case Report and Review of Literature. J Clin Exp Oncol 3:4. doi:10.4172/2324-9110.1000133


Atipic axillary mass: follicular dendritic cell sarcoma within Castleman´s disease: A Case Report and Review of Literature

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm (0.4% of soft tissue sarcomas) originating from follicular dendritic cells. On the other hand, Castleman’s disease (CD) is a rare lymphoproliferative disorder first described in 1956 by Castleman et al as a benign, localized enlargement of hyperplastic lymph nodes. Castleman´s disease has been found in association with FDCS in a minority of cases, suggesting that it may represent a precursor lesion. Combination of both FDCS and unicentric CD is extremely rare.As far as we know, there are no documented cases of a follicular dendritic cell sarcoma within a hyaline-vascular Castleman´s disease localized in the axilla.There is no consensus about treatment strategy in this situation; surgical resection when possible seems to be the best option, with or without complementary radiotherapy.We present the case of a 42-year-old male with a single axillary mass identified as a FDCS in a unicentric CD in the axilla.

Keywords: Dendritic cell; Castleman's disease

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