Journal of Virology & Antiviral ResearchISSN: 2324-8955

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Monique Lafon

Monique Lafon
Institut Pasteur- Unité de Neuroimmunologie Virale
Département de Virologie, France

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 Monique Lafon is associated with Institut Pasteur- Unité de Neuroimmunologie Virale, Département de Virologie, France. her research mainly focus on The virulence of a microbe is related to icts capacity to invade host tissues and successfully Promote icts own multiplication and dissemination. Rabies virus, a neurotropic virus That causes fatal encephalitis in mammals, HAS Developed a single strategy to Ensure icts spread into the nervous system: its virulence Correlates with icts Ability to Avoid premature apoptosis of the infected neurons and to preserve the integrity of axons / dendrites and without. Surprisingly enough, the rabies virus Does not trigger the death of the infected neurons, goal Promotes Their survival INSTEAD. Moreover, this virus sneaks through the nervous system by disarming the defenses' Mechanisms of the host. As a result, the virus can propagate and travel in the nervous system from the website of the cock up to the salivary glands From Where It Is Excreted with saliva.

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