Rand E. Simpson worked as an Asst.Professor, Department of Ophthalmology and Vision Sciences, University of Toronto. He also acts as Clinical Teacher.

 Imaging in ocular oncology and standardization of eye cancer classifications, as well as improving outcomes for eye cancer management​.

Dr. Simpson is Chair of the Research Committee for the Canadian National Institute for the Blind​ and an appointed member of the Clinical Studies Resource Centre of the Ontario Cancer Institute.