2 Author

Research Article Open Access

Clinical Efficiency of Macitentan in Patients with Pulmonary Hypertension. Real World in Argentina

Author(s):

Adrian Lescano^1,2*,

Background: Pulmonary Arterial Hypertension (PAH) is a chronic and progressive disease characterized by an increase in the pulmonary pressure and pulmonary vascular resistance that leads to high morbidity and mortality. Macitentan is an endothelin receptor antagonist (ERA), that has shown benefit in terms of morbidity and mortality (as a composite endpoint) in a randomized controlled trial (SERAPHIN), but information regarding the use of this drug in the daily clinical practice is limited in our region. Objective: To describe clinical outcomes in patients with a diagnosis of Pulmonary Hypertension (PH) treated with Macitentan in Argentina. Methods: Retrospective, observational study including adult patients with a diagnosis of PH, confirmed by right heart catheterization, who were treat... view more»

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