Amadou Alpha Salland Ousmane Faye Author

Research Article Open Access

First Identification of Orungo Virus (Orbivirus) from a Febrile Patient in South-Eastern Senegal, 2015

Author(s):

Martin Faye, Arame Ba, Yakhouba Kane, Andre Pouedewou Bedekelabou, Mamadou Diop, Moussa Moise Diagne, Gamou Fall, Oumar Faye, Amadou Alpha Sall and Ousmane Faye

Orbiviruses are of medical interest for humans and livestock worldwide. We isolated a novel Orungo virus strain from in a febrile patient living in Southeastern Senegal. The full-length genome was determined using MiSeq next-generation sequencing and the phylogenetic relationship to other orbivirus groups was analyzed. Inoculation experiments in mammalian Vero cells and mice were conducted and a specific real time reverse transcription-polymerase chain reaction assay was developed.

This is the first isolation of Orungo virus in a human in Senegal in addition to the prototype strain. This new characterized Orungo virus genome presents ten segments with the typical genomic organization of orbiviruses. However, important ami... view more»

DOI: 10.4172/2324-8955.1000187

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