Amani Elhouderi Author

Annual Meeting Abstract Open Access

Advances in HIV Ag/Ab diagnosis: ALINITY vs ARCHITECT

Author(s):

Amani Elhouderi, Yvonne Obiajulu, Panagiotis Pantelidis and Graham Pickard   

Objective: To compare and validate the performance of the new Abbott ALINITY i HIV Ag/Ab Combo assay against the current ARCHITECT HIV Ag/Ab Combo.

Method: 123 patient’s samples, previously tested on the ARCHITECT i2000 analyser, were tested on the ALINITY i system. Both instruments use chemiluminescence immunoassay technology for the qualitative detection of HIV p24 antigen and antibodies HIV type 1 and 2. All reactive and discrepant results were confirmed using a third platform (Vidas immunoassay analyzer).

Findings: 119 of the 123 HIV samples (96.7%) matched the ARCHITECT and the ALINITY. The remaining 4 discrepant samples (3.3%) were analysed by the Vidas, all of which yielded negative results, verifying th... view more»

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