Ana Cristina Goncalves Author

Research Article Subscription

Radiotherapy Effects on Immune System of Patients with Solid and Hematopoietic Tumors

Author(s):

Fernando Mendes, Catia Domingues, Paulo Rodrigues-Santos, Vera Alves, Ines-Nobre Gois, Ana Margarida Abrantes, Ana Cristina Goncalves, Mafalda Laranjo, Ana Salome Pires, Joao Casalta, Clara Rocha, Ricardo Teixo, Ana Bela Sarmento, Maria Filo

Background: Radiotherapy (RT) recruits biological effectors outside the treatment field with systemic effects. Non-cancerous cells surrounding the tumor may play a pivotal role in cancer progression, as well as in metastasis. Local radiation triggers systemic effects, which in combination with immunotherapy may contribute to better treatment outcomes.
Objective: The aim of this study was to evaluate RT effects on peripheral immune system (IS) in patients with lung cancer (LC) or diffuse large B cell lymphoma (DLBCL) after external beam radiotherapy.
Methods: We studied a group of LC and DLBCL patients i... view more»

DOI: 10.4172/2324-9293.1000124

Abstract HTML PDF