Andreas Eisenreich | Author | SciTechnol

Andreas Eisenreich Author

andreas.eisenreich@charite.de 0049 30 8445 2362 | 0049 30 8445

Subjects of specialization
microRNA,Thrombogenicity,Tissue factor,treatment of diseases,Mitochondrial DNA Damage

Affiliation
Charit

Biography

Andreas Eisenreich currently works at the Institut f�r Klinische Pharmakologie CCM, Charit� Universit�tsmedizin Berlin. Andreas does research in Cardiology. Charit� ? Universit�tsmedizin Berlin, Campus Benjamin Franklin, Centrum f�r Herz- und Kreislaufmedizin, Berlin, Germany

Publications

Research Article Open Access

Regulation of the Tissue Factor Isoform Expression and Thrombogenicity of HMEC-1 by miR-126 and miR-19a

Author(s):

Andreas Eisenreich and Ursula Rauch

Regulation of the Tissue Factor Isoform Expression and Thrombogenicity of HMEC-1 by miR-126 and miR-19a

Endothelial cells modulate the vascular wall homeostasis and blood thrombogenicity. Inflammatory conditions induce the Tissue Factor (TF) isoform expression and cellular thrombogenicity in endothelial cells. MicroRNAs (miRNAs) posttranscriptionally regulate gene expression. MiRNA-19 (miR-19) was shown to downregulate the TF expression in breast cancer cells. The role of miRNAs, such as miR-19a or the endothelial cellspecific miR-126 in the modulation of the endothelial TF expression and activity is unknown.

DOI: 10.4172/2324-9293.1000101

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