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Hindi Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541
Anselmo J Otero-Gonz?lez Author
Subjects of specialization
Affiliation
Hybridoma technology; Impact and improvements; Monoclonal antibodies
Center of Protein Studies, Faculty of Biology, Havana University, Havana City, Cuba
Biography
In 1975 George Köhler and César Milstein, with a remarkable article on hybridoma technology published in Nature, opened a new era in biology with enormous implications for analysis in biomedicine and biotechnology. It remains unquestionably important nowadays and it is basically a multifaceted methodology including procedures for antigen preparation, immunization, somatic cell fusion and cloning, cryopreservation, immunochemical screening, functional and biochemical characterization and industrial scaling up.
Publications
Review Article Open Access
38 Years of Hybridoma Technology as a Source of Analytical Tools for Immunodiagnostics of Infectious Diseases. Some Contributions Developed in Cuba to Improve the Original Procedures and Future Prospects
Author(s): Anselmo J Otero-Gonz?lez, Irelio Rodr?guez-Matheu, Octavio Luiz Franco and Jorge Sarracent-P?rez
38 Years of Hybridoma Technology as a Source of Analytical Tools for Immunodiagnostics of Infectious Diseases. Some Contributions Developed in Cuba to Improve the Original Procedures and Future Prospects
In 1975 George Köhler and César Milstein, with a remarkable article on hybridoma technology published in Nature, opened a new era in biology with enormous implications for analysis in biomedicine and biotechnology. It remains unquestionably important nowadays and it is basically a multifaceted methodology including procedures for antigen preparation, immunization, somatic cell fusion and cloning, cryopreservation, immunochemical screening, functional and bi... view more»
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