Antoniou A Author

Research Article Open Access

Multisite Pacing in Intact Myocardium and after Acute Myocardial Infarction: Experimental Study

Author(s):

Matthaios I*, Kaladaridou A, Skaltsiotes E, Agrios J, Antoniou A, Georgiopoulos G, Papadopoulou E and Toumanidis S

Background: Left ventricular (LV) pacing is unsuccessful in a significant number of patients, mainly due to sub-optimal LV pacing location. Nevertheless, data about the impact of different pacing sites on LV function in intact and ischemic myocardium are scarce.

Objectives: To investigate the effect of combinations of alternative LV pacing sites on LV mechanics, in the intact myocardium and after experimental acute anterior myocardial infarction (AMI), in order to define the optimal configuration.

Methods: Atrioventricular epicardial pacing at alternative pacing sites was performed in 16 healthy pigs simultaneously, before and after AMI. Hemodynamic parameters together with classic and novel echocardiographic indices wer... view more»

DOI: 10.4172/2324-8602.1000337

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