Endocrinology & Diabetes ResearchISSN: 2470-7570

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Audrey Boulier Author

Subjects of specialization
sucrose tolerance

Affiliation
Ingredia S.A., ARRAS, France .

Biography

Audrey BOULIER joined INGREDIA SA in 2012 after graduating from AgroParisTech, Leading French engineering Institute of Science and Food Industry Master’s degree. Currently working as Scientific and Innovative Manager for Bioactive, she manages the bioactive and nutrition scientific programs. In addition to innovative manager responsibilities, Mrs Boulier works in connections with Universities, Hospitals and Scientific Institutes in Europe. Before working for INGREDIA SA, Mrs Boulier was graduated from AgroParisTech, Leading French engineering Institute of Science and Food Industry; with a speciality on Biology Sciences and technology, Nutrition and Human food.


Publications

Annual Meeting Abstract Open Access

Dose-Effect of a 6-week treatment with PEP2DIA® on sucrose tolerance in Goto-Kakizaki (GK) rats

Author(s):

Audrey Boulier

The study was designed to evaluate the dose-effect of PEP2DIA, a patented milk protein hydrolysate on glycemic control of type 2 diabetic Goto-Kakizaki (GK) rats treated for 6 weeks from weaning. The 6 week-treatment with PEP2DIA (63mg/kg, 88.6mg/kg and 126mg/kg) did not decrease fasting plasma glucose of GK rats, but improved sucrose tolerance with the best effect at the dose of 63mg/kg. Insulin response to sucrose was lower than control after PEP2DIA treatment at all the doses tested with the strongest decrease with 63mg/kg of PEP2DIA. This decrease in insulin response seems to be at least in part the consequence of an improvement of the insulin resistance of the GK rats. At the lowest dose tested (63mg/kg), FAS and SREBP-1c gene expressions were significantly dec... view more»

Abstract PDF



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