B. O. Author

Special Issue Article Open Access

ANTI-INFLAMMATORY AND DIURETIC ACTIVITIES OF ETHANOLIC EXTRACT OF XYLOPIA AETHIOPICA (Dunal) A. Rich. (ANNONACEAE) FRUITS ON WISTAR ALBINO RAT.

Author(s):

Osuagwu, G. G. E., Osuagwu, A. N. and Kalu,  B. O.

 

This study evaluated the anti-inflammatory and diuretic activities of ethanol dried fruit extracts of Xylopia aethiopica using adult wistar albino rats as experimental model. Experiment was conducted in a Completely Randomized Design (CRD). Eighteen rats irrespective of gender were used for the study of anti-inflammatory activity and the rats were divided into six groups of three rats each. Data were analyzed using special package for social scientist (SPSS) version 20.0 and subjected to analysis of variance (ANOVA), means separation was done by Ducan multiple range test (DMRT) at 5% level of significance. The anti-inflammatory effect was evaluated on egg albumen-induced paw oedema in albino rats. A positive control containing 200mg of Aspirin and a negative control containing normal sa... view more»

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