Chamberlain I Obialo | Author | SciTechnol

Chamberlain I Obialo Author

cobialo@msm.edu (404)756-1320

Subjects of specialization
Sodium thiosulfate, Mortality

Affiliation
Renal Section, Department of Internal Medicine, Atlanta, Georgia, USA

Biography

Chamberlain I Obialo Renal Section, Department of Internal Medicine, Atlanta, Georgia, USA. His publications include:1.Janigan DT, Hirsch DJ, Klassen GA, MacDonald AS(2000) Calcified subcutaneous arterioles with infarcts of the subcutis and skin (“Calciphylaxis”) in chronic renal failure. Am J Kidney Dis 35: 588-597. 2.Fine A, Zacharias J (2002) Calciphylaxis is usually non-ulcerating: Risk factors, outcome and therapy. Kidney Int 61: 2210-2217.

Publications

Research Article Open Access

Calcific Uremic Arteriolopathy: Mortality Outcomes with and without Sodium Thiosulfate Therapy

Author(s):

Chamberlain I Obialo and Alexander Quarshie

Calcific uremic arteriolopathy (CUA) is commonly seen in patients with end stage kidney disease (ESKD) and carries a high mortality risk. Treatment with intravenous sodium thiosulfate (STS) is beneficial but its mortality advantage over therapy without STS is unknown.

We retrospectively reviewed our ESKD patient's records over a 10-year period and identified 45 biopsy confirmed cases of CUA. Associations between patients who received STS therapy and those who did not and various categorical end points were assessed using the chi-squared tests while differences in continuous end points were examined using Mann-Whitney- U tests. Multivariate logistic regression (MLR) models were used to evaluate associations between mortali... view more»

DOI: 10.4172/2576-3962.1000102

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