Chanana P Author
Subjects of specialization
Affiliation
Pharmacology, Sleep Medicine
Department of Pharmacology, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Punjab University, India
Chanana P is from Pharmacology Division, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Punjab University, India. He recently published his articles in Journal of Sleep Disorders: Treatment and Care. He reviewed many scientific papers. His research interests reflect in his wide range of publications in various national and international journals.
Research Article Subscription
Author(s): Chanana P and Kumar A
Introduction: Sleep deprivation [SD] often raises several neurological problems by causing significant alterations at multiple neural systems. Centella asiatica is a psychoactive medicinal herb with immense therapeutic potential.
Objective: The present study has been designed with aim to target mitoprotective and anti-stress pathways involved in the protective effect of Centella asiatica in addition to nitric oxide mechanism.
Methods: Male laca mice were sleep deprived for 72 hours using grid suspended over water method and Centella asiatica (150 and 300mg/kg) was administered alone and in combination with NO modulators for 8 days, starting five days before 72 hours sleep deprivation. Various behavioural (pen... view moreĀ»