Journal of Immunological Techniques & Infectious Diseases ISSN: 2329-9541

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Chang Ran Zhang Author

Subjects of specialization
Systemic lupus erythematosus; Bacille Calmette Guerin;Vaccination; Complement; Therapy; Immunology

Affiliation
Department of Internal Medicine, Huang Pu Hospital of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510700, China

Biography

Dr. Chang Ran Zhang was an assistant professor of Department of Internal Medicine, Huang Pu Hospital of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510700, China and later he started his career in Therapeutic Action Research of Bacille Calmette Guerin (BCG) on a Systemic Lupus Erythematosus Mouse Model


Publications

Research Article Open Access

Therapeutic Action Research of Bacille Calmette Guerin (BCG) on a Systemic Lupus Erythematosus Mouse Model

Author(s):

Chen biao YU, Ren Jiang, Yuan yuan Niu, Wei Shiu, Qian Gao and Chang Ran Zhang

Background: We have been determined that for patients with systemic lupus erythematosus (SLE), after becoming infected with tuberculosis, the damages in their hematologic and complement systems were alleviated to a certain extent, this was an interesting phenomenon. So we hypothesized that tuberculosis infection could be useful for treating the SLE activity.
Methods: In order to verify the above research conclusions, the animal experiments were conducted in combination with an SLE model mouse with BCG vaccinations.
Results: The research results showed that, for the mice receiving BCG vaccinations, the serum protein complement C4 concentration was significantly higher than that of the normal sal... view moreĀ»

DOI: 10.4172/2329-9541.1000150

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