Changiz Taghibiglou Author
Subjects of specialization
Affiliation
Sterol Regulatory Element ; Endoplasmic reticulum; Transcription factors; Genes; Drugs
Department of Pharmacology, College of Medicine, University of Saskatchewan, Canada
Changiz Taghibiglou Department of Pharmacology, College of Medicine, University of Saskatchewan, Canada |
Editorial Open Access
Author(s): Changiz Taghibiglou
The Sterol Regulatory Element Binding Transcription Factor 1 (SREBP1): An Attractive Therapeutic Target in CNS Drug Discoveries
Sterol regulatory element binding proteins (SREBPs) are endoplasmic reticulum (ER) residing transcription factors best known for their roles in regulation of genes mostly involved in the lipid biogenesis and metabolism in the liver and adipose tissues. This family of lipid transcription factors consists of SREBP1a, SREBP1c, and SREBP2.
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