Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653

David H. Van Thiel

Editorial Board Member

Department of Internal Medicine and Hepatology
Rush University Medical Center, USA

Contact David H. Van Thiel

Journal Impact Factor: 1.5 * ™

  Frequency: Biannually

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About the Journal

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Journal of Diagnostic Techniques and Biomedical Analysis is a peer reviewed scholarly Journal that aims to provide an academic forum for the publication of articles of various forms from research articles to case reports. All such articles reveal  the latest advancements and developments in disease diagnosis and medical analysis.

The Journal focuses on widespread dispersal of recent research developments in medical diagnosis for treating medical abnormalities through different analytical procedures, tests and techniques for the investigation, identification and monitoring of causative agents for illness or disorders.

The topics of interest encompass:

  • Disease Diagnosis
  • Medical Conditions & Diseases
  • Diagnostic Techniques
  • Biomedical Informatics
  • Laboratory Tests
  • Diagnostic Tests
  • Medical Instrumentation
  • Disease Monitoring, Treatment & Prognosis
  • Pharmaceutical Analysis
  • Infectious Diseases
  • Diagnostic Microbiology
  • Biomedical & Clinical Sciences
  • Analytical Methods
  • Radiology
  • Ultrasound
  • Biopsy
  • Chromatography
  • Computerized Axial Tomography
  • Endoscopy
  • Biomedical Imaging
  • Chemical Imaging

Articles submitted by authors are evaluated on Editorial Manager® System by a group of peer review experts in the field and it is ensured that the published articles are of high quality, reflect solid scholarship, and the information they contain is accurate and reliable. Authors may submit manuscripts and track their progress through the system. Reviewers can download manuscripts and submit their opinions and comments to the editor. Editors can manage the whole submission, review, revision and publishing process.

Submit manuscript through Editorial Manager System or Online submission or send as an e-mail attachment to the Editorial Office at [email protected] or [email protected]

Computerized Axial Tomography

Computerized Tomography is a method of examining body organs and soft tissues that cannot be seen by conventional X-Rays. It involves the scanning of organs with X rays and using a computer to construct a series of cross-sectional scans along a single axis. Computerized tomography is more commonly known by its abbreviated names, CT scan or CAT scan. A CT scan is used to define normal and abnormal structures in the body and thereby accurately assist in procedures that involve the placement of instruments or treatments. The technique is not only painless and provides extremely accurate images of body structures but also guides the radiologist in performing various procedures. Some of the procedures were CT scan plays a pivotal role are as follows: biopsies of suspected cancers, removal of internal body fluids for various tests, and the draining of abscesses which are deep in the body. CT is regarded as a moderate- to high-radiation diagnostic technique. The improved resolution of CT has permitted the development of new investigations, which may have advantages; compared to conventional radiography, for example, CT angiography avoids the invasive insertion of a catheter. Today most CT systems are capable of "spiral" (also called "helical") scanning as well as scanning in the formerly more conventional "axial" mode. The most recent advancement is that many CT systems are capable of imaging multiple slices simultaneously.

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Infectious Diseases

Infectious diseases are caused by intrusion of disease causing organisms-such as bacteria, viruses, fungi or parasites into the body followed by host-pathogen interaction leading to production of toxins that affect the body. These diseases are generally communicable diseases where the pathogenic organism spreads from one person to another either directly or indirectly. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Most common infectious diseases are of viral origin and they cause mild short-term effects, whereas other infectious diseases have the potential to cause long term or more serious effects.

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Medical Instrumentation

Medical instrumentation is the use of mechanical or electronic devices for medical diagnostic approaches.A medical device is an instrument, apparatus, implant, in vitro reagent, or similar that is used to diagnose, prevent, or treat diseases or other conditions. These devices do not achieve its purpose through chemical action on the body. Diagnosis and therapy depend heavily on the use of medical instrumentation.

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Radiology

Radiology is the specialty of medicine that deals with the study and application of imaging technology as a tool for the diagnosis and treatment of diseases. Radiology is a key part of clinical practice across a wide range of medical disciplines. It uses imaging techniques, such as X-ray radiography, magnetic resonance imaging (MRI), nuclear medicine, ultrasound, computed tomography (CT) and positron emission tomography (PET) to examine and visualize within the human body in order to diagnose abnormalities and diseases. Diagnostic radiology helps health care professionals see structures inside one’s body. Radiological procedures are medically prescribed and should only be conducted by appropriately trained and certified physicians under medically necessary circumstances. Radiologist physicians have four to six years of unique, specific, post–medical school training that includes radiation safety and ensure the optimal performance of radiological procedures and interpretation of medical images.

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Ultrasound

An ultrasound scan, is also referred to as a sonogram, diagnostic sonography and Ultrasonography, is a device that uses high frequency sound waves to create an image of some part within the body, such as the stomach, liver, heart, tendons, muscles, joints and blood vessels. Ultrasound devices generally operate with frequencies from 20 kilohertz up to several GHz. It is approximately 20 kHz in healthy, young adults and this limit varies from person to person. An instrument called a transducer emits high-frequency sound, inaudible to human ears, records the echoes as the sound waves and then bounces back to determine the size, shape, and consistency of soft tissues and organs. This information is relayed in real time to produce images on a computer screen. Ultrasound technicians, or sonographers, have special training on how to perform the test. Then a radiologist or doctor interprets the ultrasound images. Therefore this technology can help diagnose and treat certain conditions.

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Biopsy

A biopsy is the removal of a sample of tissue or cells so that they can be examined by a pathologist, usually under a microscope. There are several types of biopsies such as Fine needle aspiration biopsy, Core needle biopsy, Vacuum-assisted biopsy, Image-guided biopsy, Surgical biopsy, Bone marrow biopsy etc. Some biopsies involve removing a small amount of tissue with a needle while others involve surgically removing an entire lump or suspected tumor. Biopsies may also be performed with imaging guidance of ultrasound, x-ray, computed tomography (CT), or magnetic resonance imaging (MRI).They are most commonly performed for the insight of possible cancerous and inflammatory conditions. After performing biopsy, the sample of tissue removed from the patient is sent to the pathology laboratory and analyzed by a pathologist who is a physician well-versed in diagnosing diseases (such as cancer) by microscopical examination.

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Chromatography

Chromatography is the collective term given for a set of laboratory techniques that involve in the separation of mixtures. Chromatography has several applications, in laboratories it is used to isolate new compounds, analyze subtle differences between different environmental samples, and even in the sequencing of DNA. In any chemical or bioprocessing industry, the necessity to separate and purify a product from a complex mixture is a step of utmost importance in the production line. Today, there exists a wide market of methods in which industries can accomplish these goals. Chromatographic analysis of the serum, plasma, urine etc are extremely useful tools for the diagnosis of several metabolic disorders.

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Endoscopy

Endoscopy is the visual examination of the internal parts of a hollow body organ by use of an endoscope. The endoscope is put into the body to look inside, and is sometimes used for certain kinds of surgery. It is a nonsurgical procedure used to examine a person's digestive tract. Using an endoscope, a flexible tube with a light and camera attached to it, a doctor can view pictures of the digestive tract on a color TV monitor. Endoscopes can be passed into the large intestine (colon) through the rectum to examine this area of the intestine. This procedure is called sigmoidoscopy or colonoscopy depending on how far up the colon is examined.

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Medical Condition and Diseases

A Medical condition an abnormal state of health that interferes with the usual activities or feeling of well-being. It is also the state of illness were in the symptoms have not risen to the level of disease. Whereas a disease is resulting from a pathophysiological response to external and internal factors. Today diseases are diagnosed based on the abnormalities in systemic functions. These abnormalities can cause physical, emotional signs & symptoms, as well as pain dysfunction, distress, social problems or death.

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Laboratory Tests

Laboratory tests are prescribed by the doctor for diagnosis and detection of certain diseases or conditions. Mostly these tests are just referred for checking the viral load present like in case of Hepatitis B Virus so that the medicines can be administered accordingly to the viral load present in the patients sample.

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Analytical Methods

Analytical methods are a set of techniques that allows in measuring the composition or chemical state of a material either qualitatively or quantitatively. Analytical methods include spectroscopy, infrared spectroscopy, Raman spectroscopy, chromatography, gas chromatography, surface analysis and various other techniques.

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Disease Monitoring, Treatment & Prognosis

Disease monitoring is done by the doctor he or she may monitor or see the progression of the disease and accordingly suggest or perform the measures to be taken. Treatment can be generally referred to the first aid given to the patient but being more specific treatment is termed as the medical care, medications or injections given intravenously and intramuscularly to improve the health of patients suffering from disease. Prognosis is a prediction of the duration of a disease following its symptom .It also describes the possible outcomes of a disease and the number of times it can be expected to occur. Sometimes the symptoms of a particular patient can be useful for predicting patient's eventual outcome.

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Pharmaceutical Analysis

Pharmaceutical analysis is the analytical method used for the determination of quality and quantity of pharmaceutical products. It is a branch of practical chemistry that includes a series of experiments for identification, determination, quantification and purification of a substance, it is also used for separation of the components of a solution or mixture and also for determining structure of chemical compounds.

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Diagnostic Techniques

These techniques are procedures or methods used for recognizing the function or disability of a disease or disorder. They may be either invasive or non-invasive procedures that include laboratory tests & imaging techniques like the Radiology, Ultra sound etc. The laboratory tests include the test relating to diagnosis of infectious agents. In the diagnostic techniques that we use, two different classes can be distinguished: passive techniques (spectroscopy) and active ones. In the former case, the radiation from the plasma is studied, whereas in the latter case, some interaction with the plasma takes place, for example, a laser beam is pointed at the plasma. However the passive method of diagnosis is a very old technique. Though it is technically relatively simple the Interpretation of the results can be complicated. In case of the active techniques, they offer much more direct information about the plasma, but it  is more demanding on the experimental setup.

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Disease Diagnosis

Disease diagnosis is the identification of the nature of an illness or other problem by examination of the symptoms. It is more of a patient’s laboratory report than of the  physical examination of  the patient. The medical consultant looks for the symptoms and signs of the patient and recommends tests accordingly. Health-care professionals use symptoms and signs as clues that can help determining the most likely diagnosis when illness is present. Symptoms and signs are also used to compose a list of the possible diagnoses which is referred to as the differential diagnosis. The differential diagnosis is the basis from which initial tests are ordered to narrow the possible diagnostic options and choose initial treatments.

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Diagnostic Tests

It is the physical and psychological examination of the body as prescribed by the health care consultants. The diagnostic tests are generally of two kinds: One is laboratory tests and the other is imaging. The laboratory test contains either blood or tissue from  some part of the body being tested for disease diagnosis. Urine samples are also tested in the laboratories for confirmation of certain diseases. Imaging is generally used for the suitability of various internal body organs like bones, internal muscles, digestive systems etc. Some of the various techniques used for the testing and imaging are Nuclear resonance imaging, Radiography, Nuclear scan, Radionuclide scan etc.

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Biomedical & Clinical Sciences

Biomedical science: The application of the principles and natural sciences to medicine. It deals with the bioscience and life science I.e. any branch of the natural science which deals with the structure and behaviour of the living organism. The Biomedical scientists involves in a range of laboratory and scientific tests to support the diagnosis and treatment of disease.

clinical sciences: It is the combination of medicine, biology, chemistry, and experimental science. It's usually involves laboratory work, such as testing, evaluating, detecting and analysing cells, blood or bodily fluids. In general, clinical science is a field that evaluates and investigates medical treatments, principles and methods, using classically designed studies under controlled conditions.

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Diagnostic Microbiology

Diagnostic microbiology is a specialty in the sciences which focuses on applying microbiology to medical diagnosis. Like other microbiologists, diagnostic microbiologists tend to work in a lab environment which allows them access to a variety of equipment which they can use to identify and study the organisms they encounter. People in this field can work in labs which handle diagnostic testing for hospitals and clinics, and they can also work in research and development, helping to develop new diagnostic techniques and treatments for microbial infection.

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Biomedical Informatics

Biomedical Informatics is the science underlying the acquisition, maintenance, retrieval, and application of biomedical knowledge and information to improve patient care, medical education, and health sciences research. Biomedical informatics is the interdisciplinary, scientific field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated by efforts to improve human health.

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Biomedical imaging

Medical imaging is the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention. Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. X-ray based methods of medical imaging include conventional X-ray, computed tomography (CT) and mammography. To enhance the X-ray image, contrast agents can be used for example for angiography examinations. Molecular imaging is used in nuclear medicine and uses a variety of methods to visualize biological processes taking place in the cells of organisms. Small amounts of radioactive markers, called radiopharmaceuticals, are used for molecular imaging. Other types of medical imaging are magnetic resonance imaging (MRI) and ultrasound imaging. Unlike conventional X-ray, CT and Molecular Imaging, MRI and ultrasound operate without ionizing radiation. MRI uses strong magnetic fields, which produce no known irreversible biological effects in humans.

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Radiology

Radiology is a branch of medical science in which various forms of radiant energy are used to diagnose and treat disorders and diseases. For nearly 80 years, radiology was based primarily on the use of X rays. Since the 1970s, however, several new imaging techniques have been developed. Some, like computed tomography, makes use of X rays along with other technology, such as computer technology. Others, like ultrasound and magnetic resonance imaging, use forms of radiant energy other than X rays. Radiological techniques can also be used for therapeutic purposes, methods used to treat diseases and disorders. The use of radiology for therapy depends on the fact that X rays kill living cells. Under normal circumstances, this fact provides a good reason for people to avoid coming into contact with X rays. The destruction of healthy cells by X rays is, in fact, one of the ways in which cancers may develop.

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Biopsy research

It is the removal for diagnostic study of a piece of tissue from a living body.A biopsy is a procedure to remove a piece of tissue or a sample of cells from your body so that it can be analysed in a laboratory. If you're experiencing certain signs and symptoms or if your doctor has identified an area of concern, you may undergo a biopsy to determine whether you have cancer or some other condition.

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Chemical Imaging

Chemical imaging or vibrational hyperspectral imaging is a form of imaging in which chemical information from spectroscopy is combined with spatial information. Hyperspectral images can be collected with a single-point detector, however array detectors measure all pixels simultaneously, reduce recording time, provide uniform background, and improve the signal-to-noise ratio. This article defines chemical imaging and describes image formation and instrumentation in chemical imaging.

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