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Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Charles Coudray Author
Subjects of specialization
Affiliation
XO activity increased in chronic kidney failure, caused by adenine administration
Kassala University Kassala Campus, Kassala Sudan XO activity increased in chronic kidney failure, caused by adenine administration
Biography
XO activity increased in chronic kidney failure, caused by adenine administration Because of its high density of negatively charged phosphate groups, phytic acid (PA) forms very stable complexes with mineral ions rendering them unavailable for intestinal uptake.
Publications
Research Article Subscription
Xanthine Oxidase is Variably Involved in Nutritional and Physio-Pathologic Oxidative Stress Situations
Author(s): Christine Feillet-Coudray, Gilles Fouret, B?atrice Bonafos, Manar Aoun, Julie Carillon, Thibault Sutra, Caroline Laurent, Jean Max Rouanet, Dominique Lacan, Jean Paul Cristol and Charles Coudray
Xanthine Oxidase is Variably Involved in Nutritional and Physio-Pathologic Oxidative Stress Situations
High random ROS production leads to generalised oxidative stress that is involved in aging and degenerative diseases, such diabetes or chronic kidney failure. The major cellular ROS sources are mitochondria and NADPH oxidase, and xanthine oxidase (XO). XO is known to be involved in ischemiareperfusion oxidative stress damages, but little is known about its possible involvement in other nutritional and physio-pathologic oxidative stress situations.
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