Charles G Minard Author
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Author(s): Zeenat Safdar, Emilio Tamez, Adaani Frost1 , Danielle Guffey,Charles G Minard and Mark L Entman
Collagen Metabolism Biomarkers and Health Related Quality of Life in Pulmonary Arterial Hypertension
Objectives: The goal of this study was to investigate the association between collagen metabolism biomarkers and health related quality of life (HRQoL) in PAH patients. Methods: We prospectively enrolled 68 stable idiopathic, anorexigen-associated, and hereditary PAH subjects and 37 healthy controls. Serum samples were analyzed for N-terminal propeptide of type III procollagen (PIIINP), c-terminal telopeptide of collagen type I (CITP), matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1). The Minnesota Living with view moreĀ»