Chi-Chao Chan Author
Subjects of specialization
Affiliation
Uveitis, Ocular Immunology, Ophthalmic Pathology
Department of Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, USA
Chi-Chao Chan is from Department of Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, USA, His research interests reflect in his wide range of publications in various national and international journals
Case Report Open Access
Author(s): Shida Chen, Khurram J Malik, Defen Shen and Chi-Chao Chan
A 52 year-old male presented with acute retinal necrosis in his left eye. Slit lamp examination revealed stellate keratic precipitates and cells in the anterior chamber and vitreous. Funduscopy of his left eye revealed multiple yellow deposits. Pathological examination of the vitreous showed both small, reactive lymphocytes and a few macrophages. IL-6 and IFN-γ were elevated in the vitreous. Microdissected macrophages from the vitreous revealed DNAs from multiple viruses. The patient responded to oral valacyclovir. We conclude that multiple viral infections can be involved in the pathogenesis of acute view moreĀ»