Journal of Regenerative MedicineISSN: 2325-9620

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Connor Delman Author

cdelman@ucdavis.edu

Subjects of specialization
Cardiovascular, Tissue Engineering

Affiliation
Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, USA

Biography

Connor Delman is currently working at Department of Surgery in David Geffen School of Medicine and University of California, Los Angeles, USA. His reaserch insterst on Cardiovascular Tissue Engineering. He is an orthopedics because of the immediate impact we have on the quality of patients' lives and the camaraderie among colleagues.

Publications

Research Article Subscription

Stem Cell Extracellular Matrix Interactions in Three- Dimensional System via Integrins

Author(s): Jessica M Gluck, Connor Delman, Sean Full, Richard J Shemin and Sepideh Heydarkhan-Hagvall

Stem Cell Extracellular Matrix Interactions in Three- Dimensional System via Integrins

Cells of all types interact with the extracellular matrix (ECM) through integrin-mediated interactions. Adhesion of embryonic stem (ES) cells is necessary for differentiation. We have characterized integrin expression of undifferentiated mES cells and established a system of evaluating the ECM-integrin interactions in three-dimension (3D) using electrospun scaffolds. We observed a higher proliferation rate at early time points in conventional 2D culture with various ECM proteins (collagen IV, laminin, fibronectin, vitronectin) as compared to 3D conditions. A... view more»

DOI: 10.4172/2325-9620.1000107

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