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Hindi Journal of Clinical Immunology and Research
Dalia A Nigm Author
Subjects of specialization
Affiliation
Interleukin 25, Systemic lupus erythematous disease activity index, Systemic lupus erythematous, Lupus nephritis
Department of clinical pathology ,Faculty of medicine, Assiut University, Egypt
Biography
Dalia A Nigm Department of clinical pathology ,Faculty of medicine, Assiut University, Egypt, His Research Interest is "Pathogenesis ,MSP, PCR and the number of publications is 7
Publications
Research Article Open Access
Interleukin 25 and Systemic Lupus Erythematosus
Author(s): Dalia A Nigm and Galal MAA
Objectives: We identified that type 2 immunity stimulation has been associated with the pathogenesis of Systemic lupus Erythematous (SLE), so we studied serum level of IL 25 and its relation to SLE activity, clinical and laboratory characteristics. Methods: Serum from 90 patients who met the American College of Rheumatology (ACR) criteria for SLE and 40 healthy controls was tested for IL 25 level by Enzyme Linked Immunosorbent Assay (ELSIA). Clinical and laboratory characteristics and disease activity using SLE Disease Activity Index (SLEDAI) were also assessed. Results: IL 25 serum level was signiï¬cantly higher among SLE patients than healthy controls. It has statistically signiï¬cant correlation with disease activity. Conclusion: Our data indicates that IL 25 level is elevate... view more»
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