Dashzeveg Bayarsaihan Author
Subjects of specialization
Affiliation
Reconstructive Sciences, Regenerative Medicine, Nanotechnology to Epigenomics
Center for Regenerative Medicine and Skeletal Development, University of Connecticut Health Center, USA
Dr. Bayarsaihan received his Ph.D. from Wesleyan University and carried out postdoctoral training at Yale University. One of his research topics focuses on the molecular basis of human diseases with complex phenotype using functional genomics and animal models. Another area of interest deals with the chromatin architecture and epigenetic modifications in human and mouse neural crest stem cells. These include the global mapping studies using high resolution tiling arrays (ChIP-chip) and deep sequencing (ChIP-seq).
Editorial Open Access
Author(s): Badam Enkhmandakh and Dashzeveg Bayarsaihan
Chromatin Topology and Long- Range Genomic Interactions
The ability to reprogram somatic cells to pluripotency provides both potential opportunities for regenerative medicine, as well as an intriguing model for studying cell reprogramming. Although the generation of viable cloned mammals from adult cells is technically feasible, knowledge of such processes as chromatin reorganization, genome activation, and epigenetic modifications is necessary to gain a more thorough understanding of gene regulatory networks that govern nuclear programming. Chromatin architecture and genome wide interactions are not only altered during the transition from a somatic t... view moreĀ»