Cell Biology: Research & TherapyISSN: 2324-9293

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David A. Margolin Author

(504) 842-4000

Subjects of specialization
Rectal Surgery,Cellular Pathology,Cell Regeneration

Affiliation
Staff Colon and Rectal Surgeon and Director of Colorectal Surgery Research

Biography

Dr. David A. Margolin is a Staff Colon and Rectal Surgeon and Director of Colorectal Surgery Research at the Ochsner Clinic Foundation in New Orleans, LA. Born in Cleveland, Ohio, David received an M.D. degree from the Medical College of Ohio, Toledo.

Publications

Editorial Open Access

Are Cancer Stem Cells Responsible for Cancer Recurrence?

Author(s):

Chelsea Grimes, David A. Margolin and Li Li

Are Cancer Stem Cells Responsible for Cancer Recurrence?

Local recurrence or distant organ metastasis are the major causes of cancer mortality. Conventional treatments, including surgery, chemotherapy, and irradiation, do not consistently prevent cancer recurrence. Thus, an alternative therapeutic approach is needed. Recent evidence indicates a specific cell population of cancer stem cells or tumor initiating cells (jointly CSC) exists in various cancers that may be identified by cell surface markers, such as CD133, CD44, aldehyde dehydrogenase 1 (ALDH1) enzyme expression, or side population. 

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DOI: 10.4172/2324-9293.1000e102

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