Cell Biology: Research & TherapyISSN: 2324-9293

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Debjani Roy Author

Subjects of specialization
Biochemistry and Molecular Biology,Cell Cloning,Bioenergy,treatment of diseases,Cell therapy

Affiliation
Assistant professor of Department of Medicine, University of Medicine

Biography

https://scholar.google.com/He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.

Publications

Short Communication Open Access

MicroRNAs and epigenetics in Alzheimer’s disease: Study from the whole human genome

Author(s):

Debjani Roy

 

 

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease throughout the world. Most of the clinical symptoms of AD appear at a very later stage, therefore, the identification of disease markers is essential which can help proper detection of AD at an earlier stage and slow down its progression. Small non-coding RNAs, microRNAs (miRNAs), are modulators of gene expressions and play important roles in cellular processes. Recent studies implicate certain miRNAs in the pathogenesis of AD. Epigenetic markers such as DNA methylation and histone modification around promoter regions modify chromatin structure and regulate expression of downstream genes. Epigenetic studies have also revealed that miRNAs are directly regulated by DNA methylation and histone modification at th... view more»

Abstract PDF

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