Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653
Derek Stallard Author
Subjects of specialization
Affiliation
Opioids; Chromatography; Stationary phases; LC-MS; Column comparison; Therapeutic drug monitoring; Pain management
East Tennessee State University, Department of Chemistry, Johnson City, USA
Biography
| Derek Stallard East Tennessee State University, Department of Chemistry, Johnson City, USA |
Publications
Research Article Subscription
Comparing HPLC Stationary Phases for The Separation of Six Compounds Used in Pain Management: Is There a Viable Alternative to C18?
Author(s): Derek Stallard, Stacy Brown
Comparing HPLC Stationary Phases for The Separation of Six Compounds Used in Pain Management: Is There a Viable Alternative to C18?
In this study, four different chromatographic column chemistries (octadecylsilane/ C18, pentafluorophenyl/ PFP, octadecylated polystyrene-divinylbenzene/ PRP and underivatized silica/ HILIC) were compared under optimal conditions to evaluate the relative strengths and weaknesses of the phases for use in the determination of pain management drugs by LC-MS. Furthermore, different column scaffoldings, traditional silica, porous shell, and porous polymer, were also compared. The drugs included in this study included buprenorphine, fentanyl, methadone, naloxone, oxycodone, and tramadol. ... view more»
Google Scholars / Researchers Sites
