Doaa A. Ghareeb Author

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Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment

Author(s):

Doaa A. Ghareeb, Eman M.E. Sarhan

Role of Oxidative Stress in Male Fertility and Idiopathic Infertility: Causes and Treatment

Epidemiological studies regarding male infertility have revealed that more and more infertile men suffer from acute or chronic inflammation of the genitourinary tract, which often occurs without any symptoms. The exact mechanism for unexplained male infertility and its correlation to oxidative stress incidence and/ or the inflammatory reactions within the male genital tract is still controversially unclear till know. Previous studies have shown the presence of cytokines such as tumor necrosis factor-α (TNF-α), a key player in the inflammation process, in the semen of infertile men. However, the mechanism of their effect on human sperm functions is still in need for further... view more»

DOI: 10.4172/2469-5653.1000107

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