Eleacute;onore Catherine Michel Author
Subjects of specialization
Affiliation
Biomaterials, Carboxymethyl dextran, Québec Research Center,
Laboratory for Biomaterials and Bioengineering, CRC-I, Dept. of Min-Met- Materials Eng. & CHU de Qu
Eleacute;onore Catherine Michel Laboratory for Biomaterials and Bioengineering, CRC-I, Dept. of Min-Met- Materials Eng. & CHU de Québec Research Center, Laval University, Québec, Québec, G1V 0A6, Canada Carboxymethyl dextran; Poly(butyl methacrylate); Free radical copolymerization; Copolymers; Polymeric film; Mechanical test; Relaxation; Biomaterials
Research Article Open Access
Author(s): Eléonore Catherine Michel, Pascale Chevallier, Caroline Loy, Lucie Lévesque, Didier Letourneur and Diego Mantovani
Anti-adhesive and low-fouling properties have a particular interest in some biomedical applications to avoid non-specific cell attachments. In this work, copolymers of carboxymethyl dextran (CMD) and poly(butyl methacrylate) (PBMA) are successfully obtained by free radical copolymerization. The effects of CMD substitution degrees and CMD/BMA ratio on the copolymerization yields are investigated. Copolymers compositions are determined by carbon solid state nuclear magnetic resonance(13C-NMR), Attenuated total reflectance Fourier transform infrared spectra (ATR-FTIR) and by high performance size exclusion chromatography (HPSEC). Results indicate that copolymers are composed of CMD and a majority of PBMA, and PBMA chains are 10-fold longer than CMD ones. Solubility is investigated, and fil... view more»