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Hindi Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653
Ephrem Tesfaye Author
Subjects of specialization
Affiliation
GeneXpert MTB/RIF; Tuberculosis; Urine; Sensitivity; Specificity.
National TB and HIV Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia
Biography
| Ephrem Tesfaye National TB and HIV Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia |
Publications
Research Article Subscription
Evaluation of GeneXpert MTB/RIF® Molecular Assay Using Urine Specimen for Diagnosis of Active Pulmonary Tuberculosis from Sputum Scarce Patients in Ethiopia
Author(s): Eyob Abera Mesfin, Dereje Beyene, Abreham Tesfaye, Desalegn Addise, Miskir Amare, Biniyam Dagne, Ephrem Tesfaye, ZelalemYaregal and Belay Tessema
Backround: Tuberculosis (TB) is one of the leading causes of death in low-income countries especially among TB/HIV co-infected patients. Due to the weak health care system and difficulty of getting sputum specimens from TB-HIV co-infected patients and children, the rate of undiagnosed TB cases is very high in most high TB burden countries. Therefore, we evaluated the performance of GeneXpert MTB/RIF using urine as alternative specimen for the sputum scarce patients.
Methodology: A total of 150 clinically TB suspected cases (75 sputum scarce cases and 75 cases who were capable to provide sputum) provided a morning urine specimen and 75 cases who were able to provide sputum also provided sputum. Urine & sputum specimens were analyzed by using ... view more»
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