Everett CJ | Author | SciTechnol | Endocrinology & Diabetes Rese

Everett CJ Author

everettc@musc.edu

Subjects of specialization
Nutrition

Affiliation
US Department of Veterans Affairs, Ralph H. Johnson VA Medical Center, Charleston, SC, USA

Biography

Everett CJ US Department of Veterans Affairs, Ralph H. Johnson VA Medical Center, Charleston, SC, USA. His publications include: 1.Everett CJ, Thompson OM, Dismuke CE (2017) Exposure to DDT and diabetic nephropathy in the 1999-2004 National Health and Nutrition Examination Survey. Environmental Pollution 222: 132-137. 2.Siddarth M, Datta SK, Mustafa MD, Ahmed RS, Banerjee BD, et al. (2014) Increased level of organochlorine pesticides in chronic kidney disease patients of unknown etiology: Role of GSTM1/GSTT1 polymorphism. Chemosphere 96: 174-179.

Publications

Editorial Open Access

The Importance of Gene X Environment Interactions in Diabetic Nephropathy

Author(s):

Everett CJ

A year ago I was working on a manuscript revision for the journal Environmental Pollution. A reviewer had objected to my characterization of a finding as a case of reverse causality. I was looking at diabetic nephropathy in Mexican Americans using the 1999-2004 National Health and Nutrition Examination Survey [1]. In our study nephropathy was defined as microalbuminuria or macroalbuminuria. The data showed an odds ratio of 14.95 (95% CI 2.96-75.48) for the fourth quartile of p,p’-DDE (dichlorodiphenyldichloroethylene) compared to less than the median. DDE is a metabolite of the pesticide DDT (dichlorodiphenyltrichloroethane), and p,p’-DDE is a common isomer of DDE. I had assumed the result had to be due to reverse causality because the odds ratio was so large. For this to be... view more»

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