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Hindi Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653
Eyob Abera Mesfin Author
Subjects of specialization
Affiliation
GeneXpert MTB/RIF; Tuberculosis; Urine; Sensitivity; Specificity.
Addis Ababa University, College of Natural Sciences Department of Microbial, Cellular and Molecular Biology, Addis Ababa
Biography
| Eyob Abera Mesfin Addis Ababa University, College of Natural Sciences Department of Microbial, Cellular and Molecular Biology, Addis Ababa and National TB and HIV Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia |
Publications
Research Article Subscription
Evaluation of GeneXpert MTB/RIF® Molecular Assay Using Urine Specimen for Diagnosis of Active Pulmonary Tuberculosis from Sputum Scarce Patients in Ethiopia
Author(s): Eyob Abera Mesfin, Dereje Beyene, Abreham Tesfaye, Desalegn Addise, Miskir Amare, Biniyam Dagne, Ephrem Tesfaye, ZelalemYaregal and Belay Tessema
Backround: Tuberculosis (TB) is one of the leading causes of death in low-income countries especially among TB/HIV co-infected patients. Due to the weak health care system and difficulty of getting sputum specimens from TB-HIV co-infected patients and children, the rate of undiagnosed TB cases is very high in most high TB burden countries. Therefore, we evaluated the performance of GeneXpert MTB/RIF using urine as alternative specimen for the sputum scarce patients.
Methodology: A total of 150 clinically TB suspected cases (75 sputum scarce cases and 75 cases who were capable to provide sputum) provided a morning urine specimen and 75 cases who were able to provide sputum also provided sputum. Urine & sputum specimens were analyzed by using ... view more»
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