Galal MAA Author
Subjects of specialization
Affiliation
Interleukin 25, Systemic lupus erythematous disease activity index, Systemic lupus erythematous, Lupus nephritis
Department of Rheumatology, Rehabilitation and Physical medicine, Faculty of medicine, Assiut University, Egypt
Working at Department of Rheumatology, Rehabilitation and Physical medicine, Faculty of medicine, Assiut University, Place of living is Egypt. Subjects of Specialization are Interleukin 25; Systemic lupus erythematous; Lupus nephritis; Systemic lupus erythematous disease activity index
Research Article Open Access
Author(s): Dalia A Nigm and Galal MAA
Objectives: We identified that type 2 immunity stimulation has been associated with the pathogenesis of Systemic lupus Erythematous (SLE), so we studied serum level of IL 25 and its relation to SLE activity, clinical and laboratory characteristics. Methods: Serum from 90 patients who met the American College of Rheumatology (ACR) criteria for SLE and 40 healthy controls was tested for IL 25 level by Enzyme Linked Immunosorbent Assay (ELSIA). Clinical and laboratory characteristics and disease activity using SLE Disease Activity Index (SLEDAI) were also assessed. Results: IL 25 serum level was signiï¬cantly higher among SLE patients than healthy controls. It has statistically signiï¬cant correlation with disease activity. Conclusion: Our data indicates that IL 25 level is elevate... view more»