Journal of Clinical Immunology and Research

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Galal MAA Author

Subjects of specialization
Interleukin 25, Systemic lupus erythematous disease activity index, Systemic lupus erythematous, Lupus nephritis

Affiliation
Department of Rheumatology, Rehabilitation and Physical medicine, Faculty of medicine, Assiut University, Egypt

Biography

Working at Department of Rheumatology, Rehabilitation and Physical medicine, Faculty of medicine, Assiut University, Place of living is  Egypt. Subjects of Specialization are Interleukin 25; Systemic lupus erythematous; Lupus nephritis; Systemic lupus erythematous disease activity index


Publications

Research Article Open Access

Interleukin 25 and Systemic Lupus Erythematosus

Author(s):

Dalia A Nigm and Galal MAA

Objectives: We identified that type 2 immunity stimulation has been associated with the pathogenesis of Systemic lupus Erythematous (SLE), so we studied serum level of IL 25 and its relation to SLE activity, clinical and laboratory characteristics. Methods: Serum from 90 patients who met the American College of Rheumatology (ACR) criteria for SLE and 40 healthy controls was tested for IL 25 level by Enzyme Linked Immunosorbent Assay (ELSIA). Clinical and laboratory characteristics and disease activity using SLE Disease Activity Index (SLEDAI) were also assessed. Results: IL 25 serum level was significantly higher among SLE patients than healthy controls. It has statistically significant correlation with disease activity. Conclusion: Our data indicates that IL 25 level is elevate... view more»

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