Galina Sukoyan | Author | SciTechnol | Endocrinology & Diabetes

Galina Sukoyan Author

galinasukoian@gmail.com +995322702651

Subjects of specialization
Experimental type 2 diabetes mellitus model, NAD-containing drug

Affiliation
International Scientific Centre of Introduction of New Biomedical Technology, Tbilisi, Georgia

Biography

Galina Sukoyan International Scientific Centre of Introduction of New Biomedical Technology, Tbilisi, Georgia. His publications include: 1.Bergman M, Buysschaert, PEH Schwarz, Albright A, Yach D (2012) Diabetes prevention: global health policy and perspectives from the ground. Diab. Manage 2: 309-331. 2.Ma ZA, Zhao Z, Turk J (2012) Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus. Experimental Diabetes Research 11.

Publications

Research Article Open Access

Redox-Potential and Immune- Endothelial Axis States of Pancreases in Type 2 Diabetes Mellitus in Experiments

Author(s):

Galina Sukoyan

Abstract Background: Disturbances in mitochondrial complex1 functioning plays a crucial role in the pathogenesis of β-cells dysfunction in pancreas in diabetic mellitus (DM), and the redox-potential is a contributing factor to redox imbalance, pseudo hypoxia and chronic inflammation. The objective of this study was to assess the correlation between changes in redox-potential and inflammation response of blood and pancreases in streptozotocin (STZ)-nicotinamide (NA) induced DM in rats and ability of various pharmacological agents to its correction. Materials and methods: In randomized controlled study in rats with DM type 2 (T2DM) induced by i.p. injection of 110 mg/kg NA 15 min before intravenously injection of 65 mg/kg of STZ the redox-immune axis dist... view more»

DOI: 10.4172/2470-7570.1000129

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