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Hindi Clinical Dermatology Research JournalISSN: 2576-1439
Heena Singdia Author
Subjects of specialization
Affiliation
Dermatology, Molecular biology, Macular amyloidosis, Melanogenesis
department of dermatology, SMS Medical College, Jaipur, India.
Biography
Dr. Heena Singdia is a renowned dermatologist, working at the department of dermatology, SMS Medical College, Jaipur, India. Her main works consist of studying the basic functions of skin by measuring various biophysical parameters in various dermatological disorders. She has presented her work at various national and international conferences and has won various awards for the same.
Publications
Short Article Open Access
Macular amyloidosis pigmentation- melanin or something else, an insight into amyloid – melanin connection
Author(s): Heena Singdia
Macular amyloidosis represents a common variant of primary localized cutaneous amyloidosis (PLCA) which was first described by Palitz and Peck in 1952. Clinically, it presents as poorly delineated hyperpigmented patches of grayish-brown macules with a rippled pattern, associated with deposition of amyloid material CYTOKERATIN- 5 in the papillary dermis distributed predominantly over the interscapular area and extremities (shins and forearms) . Etiopathogenic factors - race, female gender, genetic predisposition (OSMR and IL31RA mutations), sun exposure, atopy and friction have been implicated.
Our aim was to find out the melanin content and melanin index in the lesions of Macular amyloidosis and to incure whether melanin an plays important role in... view more»
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