Ines Mahmoud Author

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Structural Effect of Tumor Necrosis Factor Inhibitors on Spine in Spondylarthritis Patients with Hip Involvement

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Ines Mahmoud

Aim: The structural efficacy of TNF alpha in spine in spondylarthrities (SpA) has been reported in several studies with prolonged follow. None of these studies did however assessed their effects in a particulary severe population of SpA with hip disease. Methods: A comparative multicenter cohort study has included two groups of SpA patients with Group 1: Patients under TNF inhibitors and group 2: TNF alpha inhibitors naive patients under conventional treatment. Clinical, biological and radiological (using mSASSS score and BASRI spine) evaluations were performed before applying anti TNF (T0), after 2 years (T2) and after a period of treatment with n ≥3 (Tn) and compared to group 2. Results: Groups 1 and 2 respectively included 24 and 21 patients. The sociodemographic and clinical char... view more»

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