Jaclyn A Biegel Author
Subjects of specialization
Affiliation
Proximal epithelioid sarcoma, Malignant extra-renal rhabdoid tumor, Multiplex ligation-dependent probe amplification, Single nucleotide polymorphism
Departments of Pediatrics and Pathology and Laboratory Medicine, Children
Jaclyn A Biegel was working at Departments of Pediatrics and Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Research Article Open Access
Author(s): Renee Frank, Navid Sadri, Tricia Bhatti, Jaclyn A Biegel, Virginia A LiVolsi and Paul J Zhang
Proximal-type epithelioid sarcoma is an aggressive variant of epithelioid sarcoma most often occurring in soft tissues of the proximal limbs, characterized by polygonal cells, marked nuclear atypia, and varied rhabdoid features. Malignant rhabdoid tumor is an aggressive, well characterized entity typically with rhabdoid morphology and involving the kidney of pediatric patients. Rarely, tumors with morphologic and biologic features identical to those in kidney occur in extra-renal sites and are regarded as an extrarenal presentation of the same entity in kidney, named malignant extra-renal rhabdoid tumor.
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