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Hindi Journal of Blood Research & Hematologic Diseases
Jafri SI Author
Subjects of specialization
Affiliation
Principle of program, Department of Curriculum, Senescence
Department of Medicine and the Carole and Ray Neag Cancer Center, University of Connecticut School of Medicine, Farmington, USA
Biography
Jafri SI, Department of Medicine and the Carole and Ray Neag Cancer Center, University of Connecticut School of Medicine, Farmington, USA. The educational objective herein is to describe 2 case reports in which patients were found to have an autoimmune disease concomitantly with a rare, benign histiocytic disorder known as Rosai-Dorfman disease (RDD). It is unclear if there is an underlying association between autoimmune disease and RDD
Publications
Case Report Subscription
Autoimmune Diseases And Rosai- Dorfman Disease Coexist More Commonly Than Expected
Author(s): Lia NL, Asad SD, Jafri SI and Harrison JS
The educational objective herein is to describe 2 case reports in which patients were found to have an autoimmune disease concomitantly with a rare, benign histiocytic disorder known as Rosai-Dorfman disease (RDD). It is unclear if there is an underlying association between autoimmune disease and RDD, as the pathophysiology of RDD has not been well defined to date. Regardless, autoimmune diseases are relatively common in the general population; hence RDD should remain within the differential diagnosis when lymphadenopathy is seen. Lymphadenopathy, although most frequently seen bilaterally in the cervical region in RDD, may present anywhere. A biopsy with histologic confirmation is required to not only evaluate for malignancy in these cases but also necessary... view more»
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