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Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Jean Max Rouanet Author
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Affiliation
XO activity increased in chronic kidney failure, caused by adenine administration
INRAE_International XO activity increased in chronic kidney failure, caused by adenine administration
Biography
XO activity increased in chronic kidney failure, caused by adenine administration Rats were fed a grape seed extract (GSE) containing (+)-catechin,(?)-epicatechin and dimers, trimers, tetramers and polymeric procyanidins. Liver, kidney, brain and gastrointestinal (GI) tract together with plasma, urine and faeces were collected
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Research Article Subscription
Xanthine Oxidase is Variably Involved in Nutritional and Physio-Pathologic Oxidative Stress Situations
Author(s): Christine Feillet-Coudray, Gilles Fouret, B?atrice Bonafos, Manar Aoun, Julie Carillon, Thibault Sutra, Caroline Laurent, Jean Max Rouanet, Dominique Lacan, Jean Paul Cristol and Charles Coudray
Xanthine Oxidase is Variably Involved in Nutritional and Physio-Pathologic Oxidative Stress Situations
High random ROS production leads to generalised oxidative stress that is involved in aging and degenerative diseases, such diabetes or chronic kidney failure. The major cellular ROS sources are mitochondria and NADPH oxidase, and xanthine oxidase (XO). XO is known to be involved in ischemiareperfusion oxidative stress damages, but little is known about its possible involvement in other nutritional and physio-pathologic oxidative stress situations.
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