Journal of Regenerative MedicineISSN: 2325-9620

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Jessica M Gluck Author

jmgluck@ncsu.edu 919-515-6637

Subjects of specialization
Stem Cell Biology, Tissue Engineering

Affiliation
Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, USA

Biography

Jessica Gluck is an Assistant Professor at Wilson College Directory,Postdoctoral Fellowship , University of California, Davis, Ph.D. Molecular, Cellular & Integrative Physiology, University of California, Los Angeles, 2013 M.S. Biomedical Engineering, University of California, Los Angeles, 2008 M.S. Biomedical Textiles, North Carolina State University, 2007 B.S. Textile Technology , North Carolina State University, 2005.

Publications

Research Article Subscription

Stem Cell Extracellular Matrix Interactions in Three- Dimensional System via Integrins

Author(s): Jessica M Gluck, Connor Delman, Sean Full, Richard J Shemin and Sepideh Heydarkhan-Hagvall

Stem Cell Extracellular Matrix Interactions in Three- Dimensional System via Integrins

Cells of all types interact with the extracellular matrix (ECM) through integrin-mediated interactions. Adhesion of embryonic stem (ES) cells is necessary for differentiation. We have characterized integrin expression of undifferentiated mES cells and established a system of evaluating the ECM-integrin interactions in three-dimension (3D) using electrospun scaffolds. We observed a higher proliferation rate at early time points in conventional 2D culture with various ECM proteins (collagen IV, laminin, fibronectin, vitronectin) as compared to 3D conditions. A... view more»

DOI: 10.4172/2325-9620.1000107

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