Jianting Li | Author | SciTechnol | Endocrinology & Diabetes Res

Jianting Li Author

jiantingli@gmail.com

Subjects of specialization
Sciences, Microbiology

Affiliation
Institute of Microbiology Chinese Academy of Sciences, Institute of Process Engineering Chinese Academy of

Biography

Institute of Microbiology Chinese Academy of Sciences, Institute of Process Engineering Chinese Academy of Sciences, Shandong University, Shanghai Jiao Tong University, University of Maryland at College Park, University of Texas at Austin

Publications

Short Communication Open Access

Metformin Influences Bile Acids to Improve the Glucose and Lipid Metabolism in Rats with Streptozotocin-induced Type 2 Diabetes Mellitus

Author(s):

Jianting Li, Yang Liu, Qiang Jiang, Lulu Wang, Rui Shi, Xiaoxia Ma, Lin Ding and Shuguang Pang

The prevalence of type 2 diabetes mellitus (T2DM), which is characterized by an increased blood glucose concentration, insulin resistance and pancreatic beta-cell dysfunction has reached epidemic proportions worldwide and represents an important threat to global public health systems [1]. On the basis of available clinical evidence, metformin has been affirmed as the first-line therapy for patients with T2DM [2]. Although a few pathophysiological mechanisms have been proposed to explain these beneficial clinical effects of metformin, detailed mechanisms of action of metformin are still not fully understood, especially its relationship with bile acids.

DOI: 10.4172/2470-7570.1000124

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