Joshua Nyagol Author

Research Article Open Access

Cytokine Expression and Hypertension Comorbidity in HIV/AIDS Patients at Kenyatta National Hospital HIV Care Centre, Nairobi, Kenya

Author(s):

Angeline Chepchirchir, Joshua Nyagol and Walter Jaoko

Chronic inflammation in HIV disease is sustained by immune reconstitution that results from use of combination therapy by patients and manifested by increased expression of inflammatory cytokines. Chronic inflammation in HIV disease is associated with endothelial dysfunction of the cardio vasculature giving rise to reduced elasticity resulting in high blood pressure. This state is marked by increased IL-6 cytokine expression as manifested in patients with type 2 diabetes and hypertension. This study sought to establish cytokine expression in HIV seropositive patients with hypertension comorbidity and correlate with HIV/AIDS progression. We hypothesized that chronic inflammation and presence of hypertension comorbidity presents higher levels of expression of ... view more»

DOI: 10.4172/2324-8602.1000343

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