Juel Chowhdury | Author | SciTechnol | Cell Biology: Research &

Juel Chowhdury Author

Subjects of specialization
Cellular Immunology,Cell Cloning,Cell Regeneration,Cell Regeneration

Affiliation
Department of Medicine, University of Medicine

Biography

He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.

Publications

Short Communication Open Access

Microsatellite instability pathway and molecular genetics of colorectal cancer

Author(s):

Juel Chowhdury,

Colorectal cancer (CRC) is a very common and lethal disease that is caused by the interaction of genetic and environmental factors. It is a stepwise process in which the genetic mutations get accumulated over time. Molecular basis of colorectal cancer has helped us to understand the key steps which lead to the advancement of tumorigenesis. There are many ways which can initiate the CRC development. CRCs are diverse genetically. Genomic instability is a crucial feature in tumor development. There are at least 3 distinct pathways in colorectal cancer pathogenesis: the chromosomal instability (CIN), microsatellite instability (MSI), and CpG island methylator phenotype (CIMP) pathways. Out of which genetical event which contributes significantly, is the microsatellite stable pathway. Micros... view more»

Abstract PDF