Junghwa Yang Author
Special Issue Article Open Access
Author(s): Junghwa Yang
Primary cutaneous cribriform carcinoma (PCCC) is a rare and under-recognized sweat gland tumor that primarily presents as a subcutaneous nodule on the extremities of middle-aged individuals. The main histopathological features are anastomosing tubules and solid nests producing a sieve-like appearance. PCCC is regarded as an apocrine tumor based on the observation of decapitation secretion in the neoplastic cells.
A 57-year-old female presented with an asymptomatic firm nodule on the back. The lesion gradually increased in size and hardened. Histopathologic examination revealed unencapsulated, circumscribed dermal nodules composed of atypical epithelial cells in a cribriform-like pattern. There were occasional atypical mitotic figures and nuclear pleomorphism of the cells withi... view moreĀ»