Katsuhisa Ikeda Author

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Peroxide Tone in Human Inferior Nasal Turbinate with Allergy

Author(s): Masato Miwa, Noritsugu Ono, Daisuke Sasaki, Akihito Shiozawa, Mayumi Miwa and Katsuhisa Ikeda

Peroxide Tone in Human Inferior Nasal Turbinate with Allergy

Background: The nose is chronically exposed to oxidative stress, which can easily lead to reactive oxygen species (ROS)-mediated damage and lipid oxidative damage of the upper airway. ROS may also participate in various diseases, including those of the airway, although many details are not yet known. ROS is generated by various enzymatic reactions and chemical processes. Superoxide dismutase (SOD), catalase, and glutathione peroxidase (GSH-Px) are representative scavengers. ROS are also generated through arachidonic acid cascades. One of the primary prostaglandins (PG), PGD2, is the major PG in most types of tiss... view more»

DOI: 10.4172/2324-8785.S1-004

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