Journal of Virology & Antiviral ResearchISSN: 2324-8955

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Kevin M. Coombs Author

kcoombs@cc.umanitoba.ca 204-789-3976

Subjects of specialization
Anti-virals, Macromolecular structure-function, Proteomics, Virus-host interactions

Affiliation
Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada

Biography

Kevin Coombs affiliated to the Department Physiology & Pathophysiology at Max Rady College of Medicine. His research intrests includes Using temperature-sensitive mammalian reovirus mutants to analyze virus assembly, Proteomic and RNAi-mediated analyses of cellular proteins involved in coronavirus, herpesvirus, influenza virus, mammalian reovirus and Zika virus replication and pathogenesis, Use of harmless mammalian reovirus as a biomarker for waste water and medical device disinfection, Mechanistic analyses of modes of action of selected anti-viral compounds.

Publications

Editorial Open Access

Fishing Beyond the Peer: Future Omic Analyses of Virus-Host Interactions

Author(s): Andrea L. Kroeker, Alicia R. Berard and Kevin M. Coombs

There has been considerable progress made in the study of viruses and how they infect, replicate and spread inside hosts and host cells. Much is known about how viruses change their genome and proteins throughout their life cycles. However, our understanding of how the host cell itself changes during the virus life cycle is less well developed. Both genomic and proteomic changes are expected to occur during virus propagation, and genomic analyses of the cellular ‘transcriptome’ have been especially fruitful during the past decade. However, our understanding of host protein responses is even more poorly developed. These –omic responses can reflect particular host metabolic pathways, such as immunological strategies, that are ctivated in response to the infecting virus.<... view more»

DOI: 10.4172/2324-8955.1000e101

Abstract HTML PDF

Google Scholars / Researchers Sites

Explore SciTechnol

GET THE APP