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Hindi Journal of Nephrology & Renal DiseasesISSN: 2576-3962
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Khan MW Author
Subjects of specialization
Affiliation
Cisplatin, Nephrotoxicity
Department of Biochemistry, Aligarh Muslim University, Aligarh, UP, India
Biography
Khan MW Department of Biochemistry, Aligarh Muslim University, Aligarh, UP, India. His publications include: 1.Fatima S, Yusufi AN, Mahmood R (2004) Effect of cisplatin on renal bruh border membrane enzymes and phosphate transport. Hum Exp Toxicol 12: 547-54. 2.Banday AA, Priyamvada S, Farooq N, Yusufi AN, Khan F (2008) Effect of uranyl nitrate on enzymes of carbohydrate metabolism and brush border membrane in different kidney tissues. Food Chem Toxicol 46: 2080-2088.
Publications
Research Article Open Access
Fish Oil Supplementation Ameliorates Long Term Cisplatin Treatment Induced Toxicity and Oxidative Damage in Rat Kidney
Author(s): Naqshbandi A, Farooqui Z, Khan MW, Rizwan S, Khan SA, Khan F and Yusufi ANK
Background: Cisplatin (CP) is an effective chemotherapeutic agent widely used against various malignancies. However, CP exerts several side effects through oxidative stress by generating reactive oxygen species (ROS). The major side effect of CP chemotherapy is dose dependent nephrotoxicity that limits its clinical usage. We have previously shown that fish oil (FO) supplementation ameliorated gentamicin induced nephrotoxicity as evident by increase in the activities of brush border membrane (BBM) and free radical scavenging enzymes in rat kidney. In the present study we aimed to investigate whether fish oil (FO) can prevent the long term CP-induced nephrotoxic effects.
Methods: Rats were ... view more»
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